Seminar Series
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February 26, 2026, 2 pm
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May 5, 2026
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Retreat
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Who can participate?
All members and associated members of FOR 5762 are warmly invited to our first retreat 2026! Where?
tba Program
tba |
Workshops
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There are currently no workshops specifically offered by FOR5762.
Please check the workshops offered by the Albertus-Magnus-Center (AMC). They offer events specific for PhD students, Postdocs and PIs. |
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Past Events
Seminar series - Prof. Bernd bukau
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Joint Seminar
FOR5762 & CRC1678 
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Many of the critical steps of enzymatic processing, membrane targeting, native folding and assembly of newly synthesized proteins occur co-translationally, implying that protein maturation and decoding of genetic information by the ribosome are coupled processes. We are using ribosome profiling technology to dissect the flux of the cellular nascent chain proteome through the system of co-translationally engaged chaperones and targeting factors. This allowed us to reveal principles of functional networking of the co-translational chaperone machineries that promote the formation of correctly folded proteins. We furthermore show that the assembly of oligomers frequently occurs co-translationally, involving the engagement of nascent subunits once the interaction domains have emerged at the ribosomal tunnel exit. We found that translation speed frequently changes at the onset of co-translational assembly, implying coordination of protein synthesis and assembly.
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coming soon
